diff --git a/crates/owlen-tui/src/chat_app.rs b/crates/owlen-tui/src/chat_app.rs
index ae92197..a355e7e 100644
--- a/crates/owlen-tui/src/chat_app.rs
+++ b/crates/owlen-tui/src/chat_app.rs
@@ -2,7 +2,7 @@ use anyhow::{Context, Result, anyhow};
 use async_trait::async_trait;
 use chrono::{DateTime, Local, Utc};
 use crossterm::{
-    event::KeyEvent,
+    event::{KeyEvent, MouseButton, MouseEvent, MouseEventKind},
     terminal::{disable_raw_mode, enable_raw_mode},
 };
 use owlen_core::consent::ConsentScope;
@@ -26,8 +26,11 @@ use owlen_core::{
 };
 use owlen_markdown::from_str;
 use pathdiff::diff_paths;
-use ratatui::style::{Color, Modifier, Style};
-use ratatui::text::{Line, Span};
+use ratatui::{
+    layout::Rect,
+    style::{Color, Modifier, Style},
+    text::{Line, Span},
+};
 use textwrap::{Options, WordSeparator, wrap};
 use tokio::{
     sync::mpsc,
@@ -95,6 +98,122 @@ const RESIZE_STEP: f32 = 0.05;
 const RESIZE_SNAP_VALUES: [f32; 3] = [0.5, 0.75, 0.25];
 const DOUBLE_CTRL_C_WINDOW: Duration = Duration::from_millis(1500);
 pub(crate) const MIN_MESSAGE_CARD_WIDTH: usize = 14;
+const MOUSE_SCROLL_STEP: isize = 3;
+
+#[derive(Clone, Copy, Debug)]
+pub(crate) struct LayoutSnapshot {
+    pub(crate) frame: Rect,
+    pub(crate) content: Rect,
+    pub(crate) file_panel: Option<Rect>,
+    pub(crate) chat_panel: Option<Rect>,
+    pub(crate) thinking_panel: Option<Rect>,
+    pub(crate) actions_panel: Option<Rect>,
+    pub(crate) input_panel: Option<Rect>,
+    pub(crate) system_panel: Option<Rect>,
+    pub(crate) status_panel: Option<Rect>,
+    pub(crate) code_panel: Option<Rect>,
+    pub(crate) model_info_panel: Option<Rect>,
+}
+
+impl LayoutSnapshot {
+    pub(crate) fn new(frame: Rect, content: Rect) -> Self {
+        Self {
+            frame,
+            content,
+            file_panel: None,
+            chat_panel: None,
+            thinking_panel: None,
+            actions_panel: None,
+            input_panel: None,
+            system_panel: None,
+            status_panel: None,
+            code_panel: None,
+            model_info_panel: None,
+        }
+    }
+
+    fn contains(rect: Rect, column: u16, row: u16) -> bool {
+        let x_end = rect.x.saturating_add(rect.width);
+        let y_end = rect.y.saturating_add(rect.height);
+        column >= rect.x && column < x_end && row >= rect.y && row < y_end
+    }
+
+    fn region_at(&self, column: u16, row: u16) -> Option<UiRegion> {
+        if let Some(rect) = self.model_info_panel {
+            if Self::contains(rect, column, row) {
+                return Some(UiRegion::ModelInfo);
+            }
+        }
+        if let Some(rect) = self.code_panel {
+            if Self::contains(rect, column, row) {
+                return Some(UiRegion::Code);
+            }
+        }
+        if let Some(rect) = self.file_panel {
+            if Self::contains(rect, column, row) {
+                return Some(UiRegion::FileTree);
+            }
+        }
+        if let Some(rect) = self.input_panel {
+            if Self::contains(rect, column, row) {
+                return Some(UiRegion::Input);
+            }
+        }
+        if let Some(rect) = self.system_panel {
+            if Self::contains(rect, column, row) {
+                return Some(UiRegion::System);
+            }
+        }
+        if let Some(rect) = self.status_panel {
+            if Self::contains(rect, column, row) {
+                return Some(UiRegion::Status);
+            }
+        }
+        if let Some(rect) = self.actions_panel {
+            if Self::contains(rect, column, row) {
+                return Some(UiRegion::Actions);
+            }
+        }
+        if let Some(rect) = self.thinking_panel {
+            if Self::contains(rect, column, row) {
+                return Some(UiRegion::Thinking);
+            }
+        }
+        if let Some(rect) = self.chat_panel {
+            if Self::contains(rect, column, row) {
+                return Some(UiRegion::Chat);
+            }
+        }
+        if Self::contains(self.content, column, row) {
+            Some(UiRegion::Content)
+        } else if Self::contains(self.frame, column, row) {
+            Some(UiRegion::Frame)
+        } else {
+            None
+        }
+    }
+}
+
+impl Default for LayoutSnapshot {
+    fn default() -> Self {
+        Self::new(Rect::new(0, 0, 0, 0), Rect::new(0, 0, 0, 0))
+    }
+}
+
+#[derive(Debug, Clone, Copy, PartialEq, Eq)]
+enum UiRegion {
+    Frame,
+    Content,
+    FileTree,
+    Chat,
+    Thinking,
+    Actions,
+    Input,
+    System,
+    Status,
+    Code,
+    ModelInfo,
+}
 
 #[derive(Debug, Clone, Copy, PartialEq, Eq)]
 enum SlashOutcome {
@@ -484,6 +603,7 @@ pub struct ChatApp {
     system_status: String,        // System/status messages (tool execution, status, etc)
     toasts: ToastManager,
     debug_log: DebugLogState,
+    last_layout: LayoutSnapshot,
     /// Simple execution budget: maximum number of tool calls allowed per session.
     _execution_budget: usize,
     /// Agent mode enabled
@@ -754,6 +874,7 @@ impl ChatApp {
             },
             toasts: ToastManager::new(),
             debug_log: DebugLogState::new(),
+            last_layout: LayoutSnapshot::default(),
             _execution_budget: 50,
             agent_mode: false,
             agent_running: false,
@@ -1872,6 +1993,14 @@ impl ChatApp {
         &self.theme
     }
 
+    pub(crate) fn set_layout_snapshot(&mut self, snapshot: LayoutSnapshot) {
+        self.last_layout = snapshot;
+    }
+
+    fn region_for_position(&self, column: u16, row: u16) -> Option<UiRegion> {
+        self.last_layout.region_at(column, row)
+    }
+
     pub fn is_debug_log_visible(&self) -> bool {
         self.debug_log.is_visible()
     }
@@ -4973,6 +5102,9 @@ impl ChatApp {
                 }
                 // Ignore paste events in other modes
             }
+            Event::Mouse(mouse) => {
+                return self.handle_mouse_event(mouse);
+            }
             Event::Key(key) => {
                 let is_ctrl_c = matches!(
                     (key.code, key.modifiers),
@@ -7631,6 +7763,171 @@ impl ChatApp {
         Ok(AppState::Running)
     }
 
+    fn handle_mouse_event(&mut self, mouse: MouseEvent) -> Result<AppState> {
+        if self.has_pending_consent() {
+            return Ok(AppState::Running);
+        }
+
+        let region = self.region_for_position(mouse.column, mouse.row);
+
+        match mouse.kind {
+            MouseEventKind::ScrollUp => {
+                if let Some(region) = region {
+                    self.handle_mouse_scroll(region, -MOUSE_SCROLL_STEP);
+                }
+            }
+            MouseEventKind::ScrollDown => {
+                if let Some(region) = region {
+                    self.handle_mouse_scroll(region, MOUSE_SCROLL_STEP);
+                }
+            }
+            MouseEventKind::Down(MouseButton::Left) => {
+                self.pending_key = None;
+                if let Some(region) = region {
+                    self.handle_mouse_click(region, mouse.column, mouse.row);
+                }
+            }
+            MouseEventKind::Drag(MouseButton::Left) => {
+                if matches!(region, Some(UiRegion::Input)) {
+                    self.pending_key = None;
+                    self.handle_mouse_click(UiRegion::Input, mouse.column, mouse.row);
+                }
+            }
+            _ => {}
+        }
+
+        Ok(AppState::Running)
+    }
+
+    fn handle_mouse_scroll(&mut self, region: UiRegion, amount: isize) {
+        if amount == 0 {
+            return;
+        }
+
+        match region {
+            UiRegion::FileTree => {
+                if self.focus_panel(FocusedPanel::Files) {
+                    self.file_tree_mut().move_cursor(amount);
+                }
+            }
+            UiRegion::Thinking | UiRegion::Actions => {
+                if self.focus_panel(FocusedPanel::Thinking) {
+                    let viewport = self.thinking_viewport_height.max(1);
+                    self.thinking_scroll.on_user_scroll(amount, viewport);
+                }
+            }
+            UiRegion::Code => {
+                if self.focus_panel(FocusedPanel::Code) {
+                    let viewport = self.code_view_viewport_height().max(1);
+                    if let Some(scroll) = self.code_view_scroll_mut() {
+                        scroll.on_user_scroll(amount, viewport);
+                    }
+                }
+            }
+            UiRegion::ModelInfo => {
+                self.scroll_model_info(amount);
+            }
+            UiRegion::Input => {}
+            UiRegion::System
+            | UiRegion::Status
+            | UiRegion::Chat
+            | UiRegion::Content
+            | UiRegion::Frame => {
+                if self.focus_panel(FocusedPanel::Chat) {
+                    self.auto_scroll
+                        .on_user_scroll(amount, self.viewport_height);
+                    self.update_new_message_alert_after_scroll();
+                }
+            }
+        }
+    }
+
+    fn handle_mouse_click(&mut self, region: UiRegion, column: u16, row: u16) {
+        match region {
+            UiRegion::FileTree => {
+                self.focus_panel(FocusedPanel::Files);
+                self.set_input_mode(InputMode::Normal);
+            }
+            UiRegion::Thinking | UiRegion::Actions => {
+                if self.focus_panel(FocusedPanel::Thinking) {
+                    self.set_input_mode(InputMode::Normal);
+                }
+            }
+            UiRegion::Code => {
+                if self.focus_panel(FocusedPanel::Code) {
+                    self.set_input_mode(InputMode::Normal);
+                }
+            }
+            UiRegion::Input => {
+                self.focus_panel(FocusedPanel::Input);
+                self.set_input_mode(InputMode::Editing);
+                if let Some(rect) = self.last_layout.input_panel {
+                    if let Some((line, column)) = self.input_cursor_from_point(rect, column, row) {
+                        let line = line.min(u16::MAX as usize) as u16;
+                        let column = column.min(u16::MAX as usize) as u16;
+                        self.textarea.move_cursor(CursorMove::Jump(line, column));
+                    }
+                }
+            }
+            UiRegion::ModelInfo => {
+                self.set_input_mode(InputMode::Normal);
+            }
+            UiRegion::System
+            | UiRegion::Status
+            | UiRegion::Chat
+            | UiRegion::Content
+            | UiRegion::Frame => {
+                self.focus_panel(FocusedPanel::Chat);
+                self.set_input_mode(InputMode::Normal);
+            }
+        }
+    }
+
+    fn input_cursor_from_point(&self, rect: Rect, column: u16, row: u16) -> Option<(usize, usize)> {
+        let lines = self.textarea.lines();
+        if lines.is_empty() {
+            return Some((0, 0));
+        }
+
+        let inner_x = usize::from(column.saturating_sub(rect.x.saturating_add(1)));
+        let inner_y = usize::from(row.saturating_sub(rect.y.saturating_add(1)));
+
+        let max_line = lines.len().saturating_sub(1);
+        let line_index = inner_y.min(max_line);
+        let column_index = Self::grapheme_index_for_visual_offset(&lines[line_index], inner_x);
+        Some((line_index, column_index))
+    }
+
+    fn scroll_model_info(&mut self, amount: isize) {
+        if amount == 0 {
+            return;
+        }
+
+        let steps = amount.unsigned_abs();
+        let viewport = self.model_info_viewport_height.max(1);
+        if amount.is_positive() {
+            for _ in 0..steps {
+                self.model_info_panel.scroll_down(viewport);
+            }
+        } else {
+            for _ in 0..steps {
+                self.model_info_panel.scroll_up();
+            }
+        }
+    }
+
+    fn grapheme_index_for_visual_offset(line: &str, offset: usize) -> usize {
+        let mut width = 0usize;
+        for (idx, grapheme) in line.graphemes(true).enumerate() {
+            let grapheme_width = UnicodeWidthStr::width(grapheme);
+            if width + grapheme_width > offset {
+                return idx;
+            }
+            width += grapheme_width;
+        }
+        line.graphemes(true).count()
+    }
+
     /// Call this when processing scroll up/down keys
     pub fn on_scroll(&mut self, delta: isize) {
         match self.focused_panel {
diff --git a/crates/owlen-tui/src/events.rs b/crates/owlen-tui/src/events.rs
index a2722dd..fcc9cd7 100644
--- a/crates/owlen-tui/src/events.rs
+++ b/crates/owlen-tui/src/events.rs
@@ -1,4 +1,4 @@
-use crossterm::event::{self, KeyCode, KeyEvent, KeyEventKind, KeyModifiers};
+use crossterm::event::{self, KeyCode, KeyEvent, KeyEventKind, KeyModifiers, MouseEvent};
 use std::time::Duration;
 use tokio::sync::mpsc;
 use tokio_util::sync::CancellationToken;
@@ -8,6 +8,8 @@ use tokio_util::sync::CancellationToken;
 pub enum Event {
     /// Terminal key press event
     Key(KeyEvent),
+    /// Mouse input event
+    Mouse(MouseEvent),
     /// Terminal resize event
     #[allow(dead_code)]
     Resize(u16, u16),
@@ -27,6 +29,7 @@ pub fn from_crossterm_event(raw: crossterm::event::Event) -> Option<Event> {
                 None
             }
         }
+        crossterm::event::Event::Mouse(mouse) => Some(Event::Mouse(mouse)),
         crossterm::event::Event::Resize(width, height) => Some(Event::Resize(width, height)),
         crossterm::event::Event::Paste(text) => Some(Event::Paste(text)),
         _ => None,
diff --git a/crates/owlen-tui/src/ui.rs b/crates/owlen-tui/src/ui.rs
index d74202c..59e6ffe 100644
--- a/crates/owlen-tui/src/ui.rs
+++ b/crates/owlen-tui/src/ui.rs
@@ -12,7 +12,9 @@ use tui_textarea::TextArea;
 use unicode_segmentation::UnicodeSegmentation;
 use unicode_width::UnicodeWidthStr;
 
-use crate::chat_app::{ChatApp, HELP_TAB_COUNT, MIN_MESSAGE_CARD_WIDTH, MessageRenderContext};
+use crate::chat_app::{
+    ChatApp, HELP_TAB_COUNT, LayoutSnapshot, MIN_MESSAGE_CARD_WIDTH, MessageRenderContext,
+};
 use crate::highlight;
 use crate::state::{
     CodePane, EditorTab, FileFilterMode, FileNode, LayoutNode, PaletteGroup, PaneId,
@@ -204,9 +206,11 @@ pub fn render_chat(frame: &mut Frame<'_>, app: &mut ChatApp) {
         .title(title_line);
 
     let content_area = main_block.inner(frame_area);
+    let mut snapshot = LayoutSnapshot::new(frame_area, content_area);
     frame.render_widget(main_block, frame_area);
 
     if content_area.width == 0 || content_area.height == 0 {
+        app.set_layout_snapshot(snapshot);
         return;
     }
 
@@ -240,6 +244,7 @@ pub fn render_chat(frame: &mut Frame<'_>, app: &mut ChatApp) {
     };
 
     if let Some(file_area) = file_area {
+        snapshot.file_panel = Some(file_area);
         render_file_tree(frame, file_area, app);
     }
 
@@ -308,25 +313,35 @@ pub fn render_chat(frame: &mut Frame<'_>, app: &mut ChatApp) {
         .split(chat_area);
 
     let mut idx = 0;
+    snapshot.chat_panel = Some(layout[idx]);
     render_messages(frame, layout[idx], app);
     idx += 1;
 
     if thinking_height > 0 {
+        snapshot.thinking_panel = Some(layout[idx]);
         render_thinking(frame, layout[idx], app);
         idx += 1;
+    } else {
+        snapshot.thinking_panel = None;
     }
     // Render agent actions panel if present
     if actions_height > 0 {
+        snapshot.actions_panel = Some(layout[idx]);
         render_agent_actions(frame, layout[idx], app);
         idx += 1;
+    } else {
+        snapshot.actions_panel = None;
     }
 
+    snapshot.input_panel = Some(layout[idx]);
     render_input(frame, layout[idx], app);
     idx += 1;
 
+    snapshot.system_panel = Some(layout[idx]);
     render_system_output(frame, layout[idx], app, &status_message);
     idx += 1;
 
+    snapshot.status_panel = Some(layout[idx]);
     render_status(frame, layout[idx], app);
 
     // Render consent dialog with highest priority (always on top)
@@ -357,14 +372,20 @@ pub fn render_chat(frame: &mut Frame<'_>, app: &mut ChatApp) {
             .x
             .saturating_add(content_area.width.saturating_sub(panel_width));
         let area = Rect::new(x, content_area.y, panel_width, content_area.height);
+        snapshot.model_info_panel = Some(area);
         frame.render_widget(Clear, area);
         let viewport_height = area.height.saturating_sub(2) as usize;
         app.set_model_info_viewport_height(viewport_height);
         app.model_info_panel_mut().render(frame, area, &theme);
+    } else {
+        snapshot.model_info_panel = None;
     }
 
     if let Some(area) = code_area {
+        snapshot.code_panel = Some(area);
         render_code_workspace(frame, area, app);
+    } else {
+        snapshot.code_panel = None;
     }
 
     if app.is_debug_log_visible() {
@@ -381,6 +402,7 @@ pub fn render_chat(frame: &mut Frame<'_>, app: &mut ChatApp) {
         }
     }
 
+    app.set_layout_snapshot(snapshot);
     render_toasts(frame, app, content_area);
 }